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HIV Transcripts in Blood May Identify Patients at Lower Risk of Brain Injury in Cure Research
(E06) CNS HIV Reservoirs
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CROI 2025 SF March 9-12
Kazuo Suzuki1,2, Angelique Levert1, Emma Yoo1, Lucette A Cysique 3,4, Takaomi Ishida5, Nicholas Olsen 6, Louise Evans7, Bruce Brew 3,8, John Zaunders 1,2
1 St Vincent's Centre for Applied Medical Research, NSW State Reference laboratory for HIV, Sydney, 2 St Vincent's Clinical School, Faculty of Medicine, Sydney, New South Wales, 3 Departments of Neurology and Immunology and Peter Duncan Neurosciences Unit, St Vincent's Hospital, Sydney, 4 UNSW Psychology, Sydney, NSW, Australia, 5 Denka Co. Ltd, Tokyo, Japan, 6 Stats Central, University of New South Wales, 7Clinical Immunology and HIV Medicine, Liverpool Hospital, NSW, Australia and UNSW Sydney, Sydney, NSW, Australia, 8 Faculty of Medicine, UNSW Sydney
"Most cure studies aim to reduce HIV DNA reservoir but may require initial viral reactivation, risking brain injury from viral blips due to reservoir activity."
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