icon-folder.gif   Conference Reports for NATAP  
 
  IDSA
ID Week 2026
October 21-24
Washington, DC

Back grey_arrow_rt.gif
 
 
 
Ten-Year Cost Projections for Medicare Beneficiaries 65 Years or Older With HIV
 

 
 
  Rising Medicare costs over the next decade must be addressed without decreasing quality of care for PWH.
 
Medicare could insure nearly 200 000 older individuals by 2035, resulting in $187.2 billion in cumulative costs to Medicare over the decade.
 
Discussion
 
In this economic evaluation using microsimulation modeling, we projected that the number of Medicare beneficiaries with HIV aged 65 or older in the US and engaged in care over the next decade would increase 1.6-fold, reaching nearly 200 000 by 2035. The financial burden on Medicare would increase substantially, with annual costs for Medicare beneficiaries aged 65 years or older increasing from $10.9 billion in 2026 to $27.3 billion in 2035. Cumulative costs over 10 years would be $187.2 billion, with 63% of that due to ART. A 60% reduction in ART costs would result in savings of $70.3 billion over 10 years compared with base case projections; drug price negotiations in the IRA or a switch to generic regimens when generic dolutegravir becomes available in the US could lead to $19.4 billion in savings.43,44
 
Key Points
 
Question Over the next decade, what will be the costs associated with Medicare beneficiaries aged 65 years or older with HIV, including antiretroviral therapy (ART) costs?
 
Findings In this economic evaluation using microsimulation modeling with 111 600 Medicare beneficiaries with HIV at model start, the number of beneficiaries aged 65 years or older receiving care for HIV is projected to increase from 121 890 at the end of 2026 to 193 560 at the end of 2035. Given current ART costs and health care-associated inflation, 10-year cumulative costs to Medicare would be $187.2 billion; however, reducing ART costs by 60% could lower Medicare spending by 38%.
 
Meaning These findings suggest that nearly 200 000 people aged 65 years or older with HIV would be enrolled in Medicare by 2035; reducing ART costs while maintaining access to high-quality ART is critical.
 
Abstract
 
Importance As the population of older people with HIV (PWH) in the US is growing, costs to Medicare are expected to rise substantially.
 
Objectives To project the number of Medicare beneficiaries aged 65 years or older receiving care for HIV in the US from 2026 to 2035 and the budget impact on Medicare.
 
Design, Setting, and Participants This economic evaluation used the Cardiovascular, HIV, Aging, Hearing Loss, Mental Health, and Dementia (CHARMED) simulation model to project the number of Medicare beneficiaries aged 65 years or older receiving care for HIV and associated costs from 2026 to 2035. The model was populated with age- and sex-stratified clinical data and costs derived from 2023 traditional Medicare claims and accounted for enrollment in Medicare Advantage, as well as health care inflation. Data analysis was conducted from September 2023 to May 2026.
 
Main Outcomes and Measures Number of Medicare beneficiaries aged 65 years or older receiving care for HIV and undiscounted costs to Medicare from 2026 to 2035.
 
Results The simulated cohort was informed by 111 600 PWH enrolled in Medicare at the start of 2026 (mean [SD] age, 70.9 [5.0] years; 77% male). The analysis found that 121 890 PWH would be enrolled in Medicare and in care by the end of 2026, including 60 390 PWH aged 65 to 69 years, 36 340 aged 70 to 74 years, 17 200 aged 75 to 79 years, and 7970 aged 80 years or older. By the end of 2035, this number would increase to 193 560, with increases in each age category (65-69 years: 70 490; 70-74 years: 62 820; 75-79 years: 38 290; 80 years and older: 21 960). Annual costs to Medicare for PWH aged 65 years or older and receiving care for HIV would increase from $10.9 billion by the end of 2026 to $27.3 billion by the end of 2035. Cumulative costs over 10 years were projected to be $187.2 billion, with 63% of cumulative costs due to antiretroviral therapy (ART). If ART costs are reduced by 60%, Medicare would save $70.3 billion over the next decade; projected savings due to the Inflation Reduction Act and generic ART would be $19.4 billion, accounting for the timing of onset and estimated reductions. Based on uncertainties in the number of Medicare beneficiaries and costs of care, sensitivity analyses found that cumulative costs would range from $103.3 billion to $267.5 billion over the next decade.
 
Conclusions and Relevance In this economic evaluation using microsimulation modeling, the number of Medicare beneficiaries aged 65 years or older receiving care for HIV was projected to increase substantially over the next decade, resulting in $187.2 billion in 10-year cumulative costs to Medicare. Reducing ART costs by 60% could lead to 38% lower overall Medicare spending for older Medicare beneficiaries with HIV.
 
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2851282