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What are the risk factors during pregnancy?
 
 
Dear Dr. Chung,
 
 
 
What are the risk factors for HCV transmission from mother to fetus during pregnancy? Does mode of delivery affect this transmission ? What is the optimal period of follow up of infants postpartum ? What is the % of seronegativity for infants ?
 
 
 
 
 
 
 
  Dr Chung Writes-  
 
 
HIV coinfection is the most important risk, raising risk to about 20% for the hiv negative mother, the risk is somewhere about 5% or less of transmission. infants should get HCV RNA testing in the first 6 months to confirm or exclude transmission. a recent study in Lancet suggested that vaginal and emergency Csections were associated with slightly higher risk than elective C section for transmission.
 
 
  RC      
 
 
 
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