iconstar paper   Hepatitis C Articles (HCV)  
Back grey arrow rt.gif
 
 
ION-1 NAIVES & ION-2 Treatment-Exp SVR Rates - RBV Cirrhotics/Ethnicity/ baseline NS5A resistance
 
 
  In ION-1 there appears no affect of with or without Rbv or 12 vs 24 weeks. But look below to ION-2 for differences.

ICAAC1.gif

ICAAC2.gif

ION-2 TREAT-Exp
 
Certain patient subgroups show a lower SVR rate without Rbv & with 12 weeks. Gt1b 2/23 87% had SVR without Rbv vs 23/23 100% with Rbv for 12 wks, but SVR rate was 100% with 24 weeks. Patients with cirrhosis had 85% w/o Rbv & 81% with Rbv with 12 weeks vs 100% (22/22 & 22/22, respectively) with 24 weeks. Ethnicity- blacks & latinos did the same with/without Rbv 12 or 24 weeks. Patients with prior therapy had better SVR rates with 24 weeks, particularly those with cirrhosis & prior experience.

ICAAC3.gif

ICAAC4.gif

ICAAC5.gif

ICAAC6.gif

 
 
 
 
  iconpaperstack View Older Articles   Back to Top   www.natap.org