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GP perceptions of liver disease; HIV & Fatty Liver/NASH
NASH Diagnosis and Management in General Practice
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Download the PDF here
EACS: Non-Alcoholic Fatty Liver Disease is a significant predictor of cardiovascular risk in HIV-mono-infected patients (12/04/19)
A gathering storm: HIV infection and nonalcoholic fatty liver disease in low and middle-income countries - (05/24/19).....HIV-associated risk factors for NAFLD are related to ART and lipodystrophy.......Reported prevalence of NAFLD and NASH in HIV ranged from 26-65 and 31-72%, respectively.....Approximately 25-30% of HIV-negative individuals with NAFLD develop NASH [8]. In HIV-positive individuals, however, the severity both at initial presentation and that of progression is higher [30]. Although there are limited data available on histopathological correlation, in a cohort of HIV-positive individuals (91% on ART) with biopsy-proven NAFLD, the prevalence of NASH was 65% and the majority had fibrosis
EACS: Fibrosis, Steatosis, and NAFLD Boost Odds of Frailty in HIV Group (11/13/19)
Tesamorelin, liver fat, and NAFLD in the setting of HIV - Comment / Tesamorelin Prevented Progression to Liver Fibrosis in NIH Study - (10/25/19)......In people living with HIV on ART, the prevalence of NAFLD is higher (26-65%)3 and they can have more severe clinical and biochemical manifestations and a faster rate of liver fibrosis progression.4
Fatty Liver in HIV+
Fatty Liver in HIV
Fatty Liver, NAFLD, NASH Definitions -
CROI: FATTY LIVER DISEASE: A GROWING CONCERN - (04/12/17) a plenary talk by noted fatty liver expert Rohit Loomba from UCSD
CROI: Changes in Liver Fibrosis and Steatosis in HIV Mono-Infected patients over 24 months - 50% have fatty liver at average age of 46 - (03/28/17)
CROI:LIVER STEATOSIS AND FIBROSIS IN AT-RISK EUROPEAN HIV-MONOINFECTED PATIENTS - 64% with steatosis among those who had elevated LFTs and/or metabolic syndrome and/or lipodystrophy - (03/28/17)
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GP perceptions of liver disease
NASH Diagnosis and Management in General Practice
(images are copyright to R. Pryke)
Rachel Pryke, MBBS MRCGP FRCP
Winyates Health Centre, United Kingdom
European workshop on NASH in Clinical Practice
webcasts, slides:
http://www.infectiousdiseasesonline.com/european-workshop-nash-clinical-practice-enduring-materials/
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