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Impact of Antiretroviral Drugs on Hypertension in HIV-positive Persons: D:A:D Study
......Hypertension in HIV+....not the ARTs...But Established/Tradional Risk Factors....age, ethnicity/Black, lipids, diabetes, lipodystrophy, BMI, eGFR, IDU
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"The most important demographic and metabolic factors independently associated with a significantly increased rate of hypertension in multivariable models are shown in Figure 3....as previously documented, established and traditional risk factors for hypertension in the general population were also confirmed for the HIV+ population in the D:A:D Study (age, ethnicity/Black, lipids, lipodystrophy, IDU, BMI, diabetes eGFR). The most important other HIV-related factors independently associated with an increased risk of hypertension are displayed in Figure 2 and were; Mode of HIV acquisition via injection drug use (IDU), previous AIDS diagnosis and a CD4 count < 200 cells/mm3......In addition to demographic and metabolic risk factors, some HIV-related factors such as mode of HIV-acquisition and low CD4 count were also significantly associated with an increased risk of hypertension."
Impact of Antiretroviral Drugs on Hypertension in HIV-positive Persons: D:A:D Study
Reported by Jules Levin
CROI 2015 Feb 23-26, Seattle, WA
CI Hatleberg1, L Ryom1, A d'Arminio Monforte2, E Fontas3, P Reiss4, O Kirk1, W El-Sadr5, S de Wit6, F Dabis7, R Weber8, M Law9, JD Lundgren1, C Sabin10
On behalf of the D:A:D Study Group
1CHIP, Department of Infectious Diseases and Rheumatology, Section 2100, Rigshospitalet - University of Copenhagen, Denmark, 2Department of Health Sciences, San Paolo University Hospital, Milan, Italy, 3Department of Public Health, Nice University Hospital, Nice, France,
4Div. of Infectious Diseases and Dept. of Global Health, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 5Mailman School of Public Health, Columbia University, New York, USA, 6Department of Infectious Diseases, CHU St.Pierre Hospital, Brussels, Belgium, 7Centre Inserm U0897-EpidŽmiologie-Biostatistique, Bordeaux, France, 8Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland, 9The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia, 10Research Department of Infection and Population Health, UCL, London, UK
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