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Fracture incidence is increased in aging HIV-infected women (WIHS) by 30% vs HIV--
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Reported by Jules Levin
CROI 2015 Feb 23-26, Seattle, WA, USA
Anjali Sharma*1, Qiuhu Shi2, Donald R Hoover3, Kathryn Anastos1, Phyllis C Tien4, Mary A Young5, Mardge Cohen6, Elizabeth T Golub7, Deborah Gustafson8, Michael T Yin9
1 Albert Einstein College of Medicine, Bronx, NY; 2New York Medical College, Valhalla, NY; 3Rutgers University, Piscataway, NJ; 4University of California San Francisco, San Francisco, CA; 5Georgetown University, Washington D.C; 6John H. Stroger, Jr. Hospital of Cook County , Chicago, IL; 7Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 8SUNY Downstate Medical Center, Brooklyn, NY; 9College of Physicians and Surgeons, Columbia University, New York , NY
"Fracture rates were higher among HIV+ than HIV- women. Cocaine and injection drug use were also significant predictors of incident fracture"
" of note age matters, every 10-year increase in age increased risk for fracture in HIV+ women by 25%, see Table 5"
"....of note, see Table 2, wrist fractures occurred more often in HIV+ women"
"Adjusted for age, race, prior fracture, and history of cocaine and injection drug use, HIV+ women had significantly higher incidence rate of any fracture compared with HIV- women - 30% higher risk -(aHR1.30; 95% CI 1.02-1.66). Among HIV+ women, older age, white race, prior fracture, smoking, and prior AIDS defining illness(aHR=1.56; 95% CI: 1.22-1.98) significantly predicted new fracture, while CD4+ count and antiretroviral exposure did not."
Reported by Jules Levin
CROI 2015 Feb 23-26, Seattle, WA, USA
Anjali Sharma*1, Qiuhu Shi2, Donald R Hoover3, Kathryn Anastos1, Phyllis C Tien4, Mary A Young5, Mardge Cohen6, Elizabeth T Golub7, Deborah Gustafson8, Michael T Yin9
1 Albert Einstein College of Medicine, Bronx, NY; 2New York Medical College, Valhalla, NY; 3Rutgers University, Piscataway, NJ; 4University of California San Francisco, San Francisco, CA; 5Georgetown University, Washington D.C; 6John H. Stroger, Jr. Hospital of Cook County , Chicago, IL; 7Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 8SUNY Downstate Medical Center, Brooklyn, NY; 9College of Physicians and Surgeons, Columbia University, New York , NY
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