ARCHIVE OF OLDER REPORTS AND DEVELOPMENTS
(Before Winter 1998)

Winter 1998 - Summer 1999

• Reports from the 3rd International Workshop on Drug Resistance and Treatment Strategies (Resistance Meeting), San Diego, June 23-26

• Resistance Testing and Prevalence of Transmitted Resistant HIV-- Report from
  Resistance Workshop, San Diego June 23 '99 (7/25/99)
  • Genotypic Testing
  • 3 Testing Companies (You want to use a reliable lab)
  • What is PhenotypicTesting?
  • Strengths & Weaknesses of Genotypic & Phenotypic Testing
  • Studies Showing Benefits of Resistance Testing -VIRADAPT
  • GART - (genotypic anti-retroviral resistance testing)
  • Prevalence of Transmitted Resistant Virus

• Nevirapine Single-Dose Reduces Transmission of HIV from Mother to Child (7/15/99)

• New Norvir (ritonavir) Soft-Gelatin Capsules Approved by FDA (June 30); Expected Availability Week of Tues. July 6 (7/4/99)  

• Nef-Deleted HIV Appears To Be Weaker—can a vaccine or therapy be developed? (6/26/99)

• New antiretroviral drugs in development which may have antiviral activity against resistant viruses in salvage situations (6/24/99)

• Herb and Drug Interactions (6/18/99)

• Interaction between Viagra (sildenafil) and HIV-1 combination therapy (6/18/99)

• New PK data on Salvage Regimen: Amprenavir+Efavirenz+Ritonavir (6/18/99)

• Very-low-fat Diet May Compromise Immunity but Increasing Fat in Diets May Maintain
  Immune System for Runners of 40 Miles per week (6/13/99)

• Three New Drugs-- HE2000, AG1459 (a new NNRTI), and AG1776 (a new protease inhibitor) (6/12/99)

• Amprenavir and Hi-Fat Meals (6/5/99)

• HIV Resistance Assays: Part 1 of a primer on resistance testing written by Johnathan Schapiro, MD, well known in resistance and clinical research of HIV. Dr Schapiro is writing this specifically for the NATAP web site. (6/5/99)

• Press Release: Abbott and Triangle Ally to Market HIV Drugs (6/5/99)  

• Researchers increasingly connect forms of HIV to monkey versions... (6/1/99)  

• A New Drug in Early Development That May Be Active Against Virus Resistant to Current Drugs (6/1/99)  

• New Fusion Inhibitor AMD-3100 Begins Phase II (6/1/99)  

• Is Eradication Possible for the Reservoir of HIV in Resting Memory CD4 cells? (6/1/99)  

• HE2000: a new HIV treatment in early research (5/12/99)  

• Dietary suggestions for taking Ritonavir Liquid (10/98)

• Study of Genotypic Resistance Testing is Starting Soon (5/27/99)

• New Fusion Inhibitors in Early Development for HIV (5/27/99)

• Researchers raise questions about prophylactic cesarean delivery to prevent Perinatal HIV transmission (5/27/99)

• Recent Information From The NIH on Stopping HAART (5/12/99)

• Trimeris' T-1249, Second HIV Fusion Inhibitor, Receives Fast Track Designation From FDA (5/99)

• Viagra Interactions with Protease Inhibitors and "Poppers" (5/99)

• New Study on Stopping PCP Prophylaxis (4/29/99)

• New Information regarding the question of T-20 resistance:

• Ultra-Sensitive Viral Load Test Approved by FDA and The Patient Assistance Program

• Researchers Report Ongoing Study Results Showing Lack of Long Term Effects of In Utero Exposure to AZT Among Uninfected Children Born to HIV-Infected Women

• HIV in Semen of Men Receiving HAART