|
- Vir Biotechnology Receives FDA Breakthrough Therapy Designation and EMA PRIME Designation for Tobevibart and Elebsiran in Chronic Hepatitis Delta - (12/18/24)
 
- AASLD:
CHARACTERIZATION OF THE DIRECT ANTIVIRAL EFFECT OF REP 2139 IN 2D AND 3D HDV INFECTION MODELS - (12/11/24)
 
- AASLD: Safety and efficacy of REP 2139-Mg in hepatitis D patients:
reporting of extended follow-up data from the international
compassionate use program - (12/11/24)
 
- AASLD: Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis Delta Receiving Bulevirtide With or Without Pegylated Interferon Alfa-2a in MYR204 - (12/04/24)
 
- AASLD: HBV/HDV Genotypes in HBV/HDV-Coinfected Patients in the United States - (12/04/24)
 
- AASLD: Similar Rates of Biochemical Response Are Observed Across Virologic Response Categories Over 96 Weeks of Bulevirtide Monotherapy in Patients With Chronic Hepatitis Delta - (12/03/24)
 
- AASLD: Real world outcomes of Hepatitis Delta patients with mild or moderate fibrosis - (12/03/24)
 
- AASLD: Efficacy and Safety of Bulevirtide Monotherapy for Chronic Hepatitis Delta: Posttreatment Results Through 48 Weeks After the End of Treatment From an Interim Analysis of a Randomized Phase 3 Study, MYR301 - (12/03/24)
 
- AASLD: Characteristics and Antiviral Treatment Patterns Among US Adults With Laboratory-Confirmed Hepatitis Delta Virus vs Hepatitis B Virus Monoinfection - (12/03/24)
 
- AASLD: BULEVIRTIDE MONOTHERAPY MAY REDUCE LIVER DECOMPENSATION IN PATIENTS WITH HDV-RELATED CIRRHOSIS: A CASE-CONTROL STUDY WITH PROPENSITY SCORE WEIGHTED ANALYSIS - (12/03/24)
 
- AASLD:
Pharmacokinetics, Pharmacodynamics, and Safety of Bulevirtide 2 mg Once Daily for 6 Days in Participants With Moderate and Severe Hepatic Impairment and in Matched Control Participants With Normal Hepatic Function - (12/03/24)
 
- AASLD: Patients With Hepatitis Delta Virus Have a Higher Risk of Disease Progression Than Patients With Hepatitis B Virus Monoinfection: Results From a Large Healthcare Provider in Israel - (12/03/24)
 
- AASLD:
Patient-Reported Outcomes Among Patients With Chronic Hepatitis Delta Treated With Bulevirtide 2 mg: A Long-Term Analysis of the Phase 3 MYR301 Trial at 144 Weeks - (12/03/24)
 
- AASLD: Association of Hepatitis Delta Virus (HDV) Infection and Hepatocellular Carcinoma, Decompensation, All-cause and Liver-Related Death in a US National Cohort - (12/03/24)
 
- AASLD:
LONG-TERM BULEVIRTIDE MONOTHERAPY IN PATIENTS WITH HDV-RELATED COMPENSATED CIRRHOSIS: EFFECTIVENESS, SAFETY AND CLINICAL OUTCOMES FROM THE RETROSPECTIVE MULTICENTER EUROPEAN STUDY (SAVE-D) - (12/03/24)
 
- AASLD: BJT-778, anti-HBsAg monoclonal antibody, achieved 100% virologic response in subjects with chronic hepatitis D (CHD): phase 2 study results - (12/03/24)
 
- AASLD:
Vir Biotechnology Presents Positive Chronic Hepatitis Delta Clinical Trial Data and Announces Initiation of Phase 3 Registrational Program
- (12/03/24)
 
- AASLD: Vir Biotechnology Receives Positive Opinion on Orphan Drug Designation for Tobevibart and Elebsiran in Chronic Hepatitis Delta from European Medicines Agency - (12/03/24)
 
- AASLD:
Positive Chronic Hepatitis Delta Clinical Trial Data and Announces Initiation of Phase 3 Registrational Program - (12/03/24)
 
- AASLD: Tobevibart (VIR-3434) and Elebsiran (VIR-2218) With or Without
Pegylated Interferon Alfa-2a for the Treatment of Chronic HBV Infection:
End of Treatment Results After 48 Weeks of Therapy (MARCH Study) - (12/03/24)
 
- AASLD: Efficacy and Safety of Tobevibart (VIR-3434) Alone or in Combination With Elebsiran (VIR-2218) in Participants With Chronic Hepatitis Delta Virus Infection: Week 24 Primary Endpoint Analysis From the Phase 2 SOLSTICE Trial - (12/03/24)
 
- ID Week: Predictors of Undetectable HDV RNA 48 Weeks After Completion of Finite Treatment With Bulevirtide and Pegylated-Interferon Alpha-2a - (10/24/24)
 
- ID Week:
Efficacy and Safety of Bulevirtide Monotherapy for Chronic Hepatitis Delta in Patients With and Without Cirrhosis: Results From the Week 144 Interim Analysis of a Phase 3 Randomized Study - (10/24/24)
 
- HEPATITIS D INFECTION: who should be screened AASLD 2018 HBV Guidelines - (05/27/22)
 
- Hepatitis D Changing Context Global Prevalence - (02/10/22)
 
- EASL: Efficacy and Safety of Bulevirtide Monotherapy Given at 2 mg or 10 mg Dose Level Once Daily for Treatment of Chronic Hepatitis Delta: Week 48 Primary Endpoint Results From a Phase 3 Randomized, Multicenter, Parallel Design Study - (06/24/22)
 
- EASL: Robust reduction of HBsAg and HDV RNA levels with low risk for ALT elevations in JNJ-73763989 treated patients with chronic hepatitis D (CHD) and baseline HBsAg levels below 10,000 IU/mL: Part 2 of the REEF-D study
- (06/18/24)
 
- EASL: Pharmacokinetics and Safety of Single Dose of the Monoclonal Antibody Tobevibart (VIR-3434) Administered as Monotherapy or in Combination with the Small Interfering RNA Elebsiran (VIR-2218) in Cirrhotic Participants with Mild Hepatic Impairment
- (06/18/24)
 
- EASL HDV infection in Israel: Epidemiology and co-morbidities
- (06/18/24)
 
- EASL Efficacy and safety of tobevibart (VIR-3434) alone or in combination with elebsiran (VIR-2218) in participants with chronic hepatitis delta virus infection: preliminary results from the phase 2 SOLSTICE trial in non-cirrhotic and compensated cirrhotic participants
- (06/18/24)
 
- EASL The burden of chronic hepatitis delta in Italy: potential impacts and effects of bulevirtide through Cost of Illness and Cost Consequence Analysis
- (06/14/24)
 
- EASL Healthcare Resource Utilisation and Costs of Hepatitis Delta Virus Infection vs Hepatitis B Virus Monoinfection Across Disease States Among Hospitalised Adults in Italy
- (06/14/24)
 
- EASL Bulevirtide Monotherapy Lowers Risk of Decompensation But Not HCC
- Mark Mascolini (06/14/24)
 
- EASL The underestimated burden of hepatitis D among people living with chronic hepatitis B in the Gambia
- (06/14/24)
 
- EASL
Tobevibart (VIR-3434), a Monoclonal Antibody, Resistance Analysis in Participants With Chronic HBV: Results From a Phase 1, Single-dose Study
- (06/14/24)
 
- EASL Pharmacokinetics and Safety of Single Dose of the Monoclonal Antibody Tobevibart (VIR-3434) Administered as Monotherapy or in Combination with the Small Interfering RNA Elebsiran (VIR-2218) in Cirrhotic Participants with Mild Hepatic Impairment
- (06/14/24)
 
- EASL Efficacy and safety of tobevibart (VIR-3434) alone or in combination with elebsiran (VIR-2218) in participants with chronic hepatitis delta virus infection: preliminary results from the phase 2 SOLSTICE trial in non-cirrhotic and compensated cirrhotic participants
- (06/14/24)
 
- EASL
Pre- and Post-Bulevirtide Biopsies Show HDV RNA Drops in Liver Track With Drops in Blood
- (06/13/24)
 
- EASL Pre- and Post-Bulevirtide Biopsies Show HDV RNA Drops in Liver Track With Drops in Blood
- Mark Mascolini (06/13/24)
 
- EASL Preclinical Profiling of ABI-6250, a Novel Orally Bioavailable Small-Molecule Therapeutic Candidate for the Treatment of Chronic Hepatitis
- (06/13/24)
 
- EASL No Amino Acid Substitution in HBV Pres1, HDAg, Or NTCP Associated With Suboptimal Response to Bulevirtide in Combination With Pegylated Interferon Alfa-2a Treatment in Participants With Chronic Hepatitis Delta: Results From MYR204, a Phase 2b Study
- (06/13/24)
 
- EASL Efficacy and Safety of 144 Weeks of Bulevirtide 2 mg or
10 mg Monotherapy From the Ongoing Phase 3 Study MYR301
- (06/13/24)
 
- EASL Bulevirtide monotherapy prevents liver decompensation and reduces mortality in patients with HDV-related cirrhosis: a case control study with propensity score weighted analysis
- (06/13/24)
 
- EASL
LONG-TERM VIROLOGICAL AND CLINICAL OUTCOMES OF PATIENTS WITH HDV-RELATED CIRRHOSIS TREATED WITH BULEVIRTIDE MONOTHERAPY FOR UP TO 120 WEEKS: A RETROSPECTIVE MULTICENTER EUROPEAN STUDY (SAVE-D)
- (06/13/24)
 
- EASL
Sustained virological response after treatment with Bulevirtide in HDV patients. Data from the french multicenter real-life cohort
- (06/13/24)
 
- EASL
Bulevirtide in combination with pegylated interferon alfa-2a
shows a sustained off-treatment response in the liver
- (06/13/24)
 
- EASL
Unique Characteristics and Risk of Liver-Related Events Among Individuals With Hepatitis Delta Virus Infection With and Without Concurrent Hepatitis C Virus Infection: A United States Administrative Claims Data Analysis
- (06/13/24)
 
- EASL
Anti-HDV and HDV RNA Testing Rates for Hepatitis Delta Virus Among Adult Patients in the United States
- (06/13/24)
 
- EASL
Bulevirtide efficacy and safety in chronic hepatitis D patients on liver transplant waiting list for decompensated cirrhosis and/or hepatocellular carcinoma
- (06/13/24)
 
- EASL High frequency of liver cirrhosis in European patients with hepatitis D: First data from a large multicentre study (D-SOLVE and HDV-1000 consortia)
- (06/13/24)
 
- EASL Rapid Reductions of HDV RNA and ALT with the Monoclonal Antibody, BJT-778: Results from a Phase 2 Study
- (06/13/24)
 
- EASL Safety and efficacy of REP 2139-Mg in hepatitis D patients with advanced liver disease: an international compassionate use program
- (06/12/24)
 
- EASL Undetectable HDV RNA Defined as Target Not Detected at the End of Treatment With Bulevirtide and/or Pegylated Interferon Alpha-2a Is an Important Predictor of 48 Weeks Sustained Virologic Response in Chronic Hepatitis Delta
- (06/12/24)
 
- EASL
Bulevirtide Plus pegIFNα Superior
to Bulevirtide Alone for Chronic HDV
- Mark Mascolini (06/12/24)
 
- EASL Undetectable HDV RNA at 24 Weeks of Treatment With Bulevirtide and Pegylated Interferon Alfa-2a Combination Therapy Is an Important Predictor of Maintained Response Off-Therapy
- (06/12/24)
 
- EASL
Impact of Bulevirtide Given With or Without Nucleos(t)ide Analogues
on 48-Week Virologic Outcomes in Patients With Chronic Hepatitis Delta Virus Infection
- (06/12/24)
 
- EASL Improvement in Liver Histology Is Observed in Most Patients With
Chronic Hepatitis Delta After 48 Weeks of Bulevirtide Monotherapy
- (06/11/24)
 
- EASL Bulevirtide Plus pegIFNα
Superior to Bulevirtide Alone for Chronic HDV
- Mark Mascolini (06/11/24)
 
- EASL Hepatitis Delta Virus Infection is Associated with Significantly Greater Incidence of Cirrhosis and Hepatic Decompensation in U.S. Veterans with Chronic Hepatitis B
- (06/11/24)
 
- EASL
Bulevirtide Combined with Pegylated Interferon for Chronic Hepatitis D
- (06/11/24)
 
- EASL
48-Week Off-Therapy Efficacy and Safety of Bulevirtide in Combination with Pegylated Interferon Alfa-2a in Patients with Chronic Hepatitis Delta: Final Results from the Phase 2b, Open-Label, Randomised, Multicentre Study MYR204
- (06/11/24)
 
- EASL: LONG-TERM VIROLOGICAL AND CLINICAL OUTCOMES OF PATIENTS WITH HDV-RELATED CIRRHOSIS TREATED WITH BULEVIRTIDE MONOTHERAPY FOR UP TO 120 WEEKS: A RETROSPECTIVE MULTICENTER EUROPEAN STUDY (SAVE-D) - (06/08/24)
 
- EASL: Sustained virological response after treatment with Bulevirtide in HDV patients. Data from the french multicenter real-life cohort - (06/08/24)
 
- DDW: HIGH RATES OF ADHERENCE TO BULEVIRTIDE MONOTHERAPY FOR CHRONIC HEPATITIS DELTA THROUGH 96 WEEKS: RESULTS FROM AN INTERIM ANALYSIS OF THE PHASE 3 STUDY MYR301 - (05/21/24)
 
- DDW: NON-INVASIVE TESTING IN CHRONIC HEPATITIS D VIRUS
(HDV) INFECTION: WHAT WORKS BEST TO RULE OUT CIRRHOSIS? - (05/21/24)
 
- DDW: EFFICACY AND SAFETY AT 96 WEEKS OF BULEVIRTIDE 2 MG OR 10 MG MONOTHERAPY FOR CHRONIC HEPATITIS DELTA: RESULTS FROM AN INTERIM ANALYSIS OF A PHASE 3 RANDOMIZED STUDY - (05/21/24)
 
- New WHO HBV Treatment Recommendations, HDV Too;
HCC monitoring; mother-to-child HBV transmission prevention - (04/15/24)
 
- CROI:
Summary from CROI 2024 for HIV and liver disease - Jurgen K. Rockstroh M.D., Professor of Medicine
University of Bonn, Germany - (03/25/24)
 
- CROI:
Epidemiologic Burden of Hepatitis D Virus in the United States - (03/28/24)
 
- CROI:
INCIDENCE AND OUTCOME OF HDV INFECTION
IN PEOPLE WITH HIV IN THE ERA OF TENOFOVIR-CONTAINING THERAPY - (03/28/24)
 
- CROI: Efficacy and Safety of Bulevirtide 2 mg or 10 mg for 96 Weeks in Chronic Hepatitis Delta, Including in 2 Patients With HIV/Hepatitis B Virus/Hepatitis Delta Virus - (03/28/24)
 
- CROI: lntrahepatic HDV activity is fueled by integrated HBV DNA-derived HBs independently from cccDNA size/a> - (03/27/24)
 
- AASLD: Epidemiological and Clinical Characteristics of HBV and HDV Co-infected Patients Followed by the Canadian HBV Network - (11/20/23)
 
- AASLD:
A 5-YEAR SNAPSHOT OF NATIONAL DELTA HEPATITIS SCREENING IN METROPOLITAN FRANCE: DELTA DESCRIBE - DATA ISSUED FROM THE FRENCH HEALTH INSURANCE - (11/20/23)
 
- AASLD: Baseline Characteristics of Hepatitis Delta Patients Enrolled Across Phase 2 and 3 Studies of Bulevirtide
- (11/20/23)
 
- AASLD: Relationship Between ALT Normalization Rates and Different Virologic Response Criteria in Chronic HDV Patients Treated With Bulevirtide Monotherapy - (11/20/23)
 
- AASLD: The need for caregiver support in patients with hepatitis D virus infection: descriptive results from a real-world survey in Germany, Italy, Spain and the United States of America - (11/20/23)
 
- AASLD: Development of Antidrug Antibodies on Bulevirtide Monotherapy in Chronic Hepatitis Delta Does Not Impact Bulevirtide Efficacy, Safety, or Pharmacokinetics - (11/20/23)
 
- AASLD: HDV persists in human hepatocytes undergoing cell division in human liver chimeric mice but is potently inhibited by pegylated interferon-alpha treatment - (11/19/23)
 
- AASLD: Hepatitis Debrief at AASLD 2023 (HCV, HBV, HDV), Jennifer Price MD - (11/15/23)
 
- AASLD: Liver-related Complications in Patients with HDV Higher
than in HBV Mono-Infected Patients: A Regional NYC-Based Assessment - (11/15/23)
 
- AASLD: LIVER STIFFNESS MEASUREMENT TO DETECT SEVERE FIBROSIS
AND CIRRHOSIS IN PATIENTS WITH CHRONIC HEPATITIS D INFECTION - (11/15/23)
 
- AASLD: The monoclonal antibody VIR-3434 and siRNA VIR-2218 for the treatment of chronic Hepatitis D Virus: preliminary results from the Phase 2 SOLSTICE trial - (11/15/23)
 
- AASLD:
Efficacy and Safety of Bulevirtide in Combination with Pegylated Interferon alfa-2a in Patients with Chronic Hepatitis Delta: Primary Endpoint Results from a Phase 2b Open-Label, Randomized, Multicenter Study MYR204 - (11/15/23)
 
- AASLD: Results From an Integrated Analysis at Week 96: Continued Treatment of Early Virologic Non-responders or Partial Responders With Bulevirtide Monotherapy for Chronic Hepatitis Delta Leads to Improvement in Virologic and Biochemical Responses - (11/15/23)
 
- AASLD: Low HEPATITIS DELTA TESTING TRENDS IN A U.S. NATIONAL COHORT (2000-2022): AN ANALYSIS OF PATIENT AND PROVIDER-LEVEL PREDICTIVE FACTORS - (11/15/23)
 
- AASLD:
Occurrence of Liver-Related Events in Individuals With Hepatitis Delta Virus: A Systematic Review - (11/15/23)
 
- AASLD: Burden of Hepatitis D Virus infection in Italy:
interim analysis from a prospective multicentre nationwide study - (11/14/23)
 
- AASLD:
Health Care Resource Utilization and Costs of HDV Infection
vs HBV Monoinfection Across Disease States in a Hospital Records Database From Spain - (11/14/23)
 
- AASLD: HDV Superinfection Doubles Risk of HCC Versus HBV Infection Alone - Mark Mascolini (11/14/23)
 
- AASLD:
National and Regional Prevalence of Hepatitis
Delta Virus Among Commercially Insured Patients in the US - (11/14/23)
 
- AASLD: VIR-2218 and VIR-3434 Therapy Is Efficacious in Preclinical Models of Hepatitis Delta Virus Infection - (11/13/23)
 
- AASLD:
Prevalence of Hepatitis B and D Virus Among a Nationally
Representative Insured Population in the United States - (11/13/23)
 
- AASLD: UNDERSTANDING THE ANTIVIRAL EFFECTS OF PEGINTERFERON LAMBDA WITH AND WITHOUT RITONAVIR BOOSTED LONAFARNIB IN CHRONIC HEPATITIS D INFECTION - (11/13/23)
 
- AASLD:
BASELINE PREDICTORS OF VIROLOGICAL AND BIOCHEMICAL RESPONSES IN HDV COMPENSATED CIRRHOTIC PATIENTS TREATED WITH BULEVERTIDE MONOTHERAPY (HEP4Di STUDY) - (11/13/23)
 
- AASLD: BULEVIRTIDE IN PATIENTS WITH NON-COMPENSATED LIVER CIRRHOSIS DUE TO HEPATITIS D - (11/13/23)
 
- AASLD:
Improvement in Noninvasive Markers of Fibrosis (LSM, FIB-4, and APRI)
Is Seen Over 96 Weeks of Bulevirtide Monotherapy in Chronic Hepatitis
Delta Regardless of Virologic Response - (11/13/23)
 
- AASLD: Bulevirtide: Treatment for Hepatitis D and Beyond USA Status - (11/13/23)
 
- AASLD: No Detectable Resistance to Bulevirtide Monotherapy Through 96 Weeks Treatment in Patients With Chronic Hepatitis Delta - (11/13/23)
 
- EACS:
HDV Prevalence 16% in French Group With HBV and HIV - Mark Mascolini (10/26/23)
 
- IAS: Hepatitis delta and liver disease among people living with hepatitis B in Senegal - (08/14/23)
 
- EASL: Estimating the Prevalence of Hepatitis Delta
Infection among Foreign-Born Adults with Chronic Hepatitis B
in the United States
- (07/05/23)
 
- EASL: Impact of the anti-HDV reflex testing on the reduction of hepatitis D burden in Spain
- (07/05/23)
 
- EASL:
Low coverage of hepatitis D virus testing in individuals with
HIV and HBV in the Netherlands (ATHENA): a retrospective, cross-sectional
and longitudinal study
- (07/05/23)
 
- EASL:
Prevalence (15%) and incidence of delta hepatitis in HIV-HBV coinfected patients in the Dat'AIDS (French) cohort
- (07/05/23)
 
- EASL: An international coalition to eliminate hepatitis B virus (ICE-HBV) survey confirms inadequate HBV/HDV screening and diagnosis diminishing elimination targets in resource limited settings
- (07/05/23)
 
- EASL: Off-label Bulevirtide monotherapy for chronic hepatitis D
virus infection in patients with decompensated liver disease
- (07/05/23)
 
- EASL: Five years follow-up of 96 weeks peginterferon plus tenofovir disoproxil fumarate in hepatitis D
- (07/05/23)
 
- EASL: Long-term outcome of hepatitis delta in different
regions world-wide: Results of the Hepatitis Delta International Network (HDIN) - (07/03/23)
 
- EASL:
Fast Response to REP 2139-Mg in 3 With HDV/HBV and Decompensated Cirrhosis - Mark Mascolini (06/30/23)
 
- EASL: Treatment with siRNA JNJ-73763989 plus nucleos (t)ide analogue (NA) decreases HBsAg and HDV RNA levels in patients with chronic hepatitis D (CHD): part 1 of the REEF-D study - (06/30/23)
 
- EASL:
Concomitant use of Proton Pump Inhibitors and Sofosbuvir/Velpatasvir:
Evidence from Randomized Clinical Trials and Real-World Data - (06/30/23)
 
- EASL:
Population Adjusted Prevalence of Hepatitis Delta Virus in 21 Countries and Territories - (06/29/23)
 
- EASL:
A Phase 3, Randomized Trial of Bulevirtide in Chronic Hepatitis D - (06/29/23)
 
- EASL:
Lonafarnib With Ritonavir Slows HDV in 48-Week Placebo Trial - Mark Mascolini (06/29/23)
 
- EASL: HDV Full Genome Sequencing and Sensitive HBV
Genotyping from a Large Cohort of HBV/HDV Co-infected Patients - (06/29/23)
 
- EASL: The impact of hepatitis D virus infection on health-related quality of life and fatigue in patients untreated for HDV: Descriptive results from a cross-sectional study across Italy, Germany, Spain and the US - (06/29/23)
 
- EASL:
Qualitative interviews to assess the impact of chronic hepatitis delta virus infection on health-related quality of life in untreated patients from the US, Italy, Spain, and Germany - (06/29/23)
 
- EASL: Liver stiffness measurement as a noninvasive method for the diagnosis of liver cirrhosis in patients with chronic hepatitis D virus infection - (06/29/23)
 
- EASL:
Hepatitis Delta Treatment Utilization in the United States:
An Analysis of Commercially Insured Adults With Hepatitis Delta Virus Infection
- (06/29/23)
 
- EASL: Significantly Higher Clinical and Economic Burden Following Diagnosis of Hepatitis Delta Virus Infection Among Commercially Insured Adults With Chronic Hepatitis B in the United States - (06/29/23)
 
- EASL: Healthcare Resource Use and Costs Associated With Hepatitis Delta Virus Infection Compared With Hepatitis B Virus Monoinfection Among Commercially Insured Patients in the US - (06/29/23)
 
- EASL: Increased Baseline Comorbidity Burden Among Commercially Insured Patients With Hepatitis Delta Virus Infection vs Hepatitis B Virus Monoinfection in the United States
- (06/29/23)
 
- EASL: Increased Baseline Comorbidity Burden Among
Commercially Insured Patients With Hepatitis
Delta Virus Infection vs Hepatitis B Virus
Monoinfection in the United States
- (06/26/23)
 
- EASL: A Retrospective Observational Cohort Study of Liver-Related Events Among Patients With Hepatitis B Virus Infection With and Without Hepatitis Delta Virus Infection
- (06/26/23)
 
- EASL: Week 48 results of the phase 3 D-LIVR study, a randomized double-blind, placebo-controlled trial evaluating the safety and efficacy of Lonafarnib-boosted with Ritonavir with or without Peginterferon Alfa in patients with chronic hepatitis delta
- (06/26/23)
 
- EASL: HDV-RNA decline less than 1 log after 6 months of BLV 2 mg monotherapy could define poor-response and lead to therapeutic decision.
- Mark Mascolini (06/26/23)
 
- EASL: HDV-RNA decline less than 1 log after 6 months of BLV 2 mg monotherapy could define poor-response and lead to therapeutic decision. Data from real-life cohort
- (06/26/23)
 
- EASL: Efficacy and safety at 96 weeks of bulevirtide 2 mg or 10 mg monotherapy for chronic hepatitis D: results from an interim analysis of a phase 3 randomized study
- (06/26/23)
 
- EASL:
Patients With Chronic Hepatitis Delta Virus Infection Have Higher Risk of Disease Progression Than Chronic Hepatitis B Virus Monoinfection-Results From a Spanish National Hospital Database
- (06/26/23)
 
- EASL:
Stopping Bulevirtide After Long-Term HDV Control Appears Safe With Close Monitoring
- Mark Mascolini (06/26/23)
 
- EASL:
SIGNIFICANT IMPROVEMENT OF NON-INVASIVE FIBROSIS TESTS IN HDV COMPENSATED CIRRHOTIC PATIENTS WITH CLINICALLY SIGNIFICANT PORTAL HYPERTENSION TREATED WITH BLV MONOTHERAPY UP TO 96 WEEKS
- (06/26/23)
 
- EASL: VIROLOGICAL AND CLINICAL OUTCOMES OF PATIENTS WITH
HDV-RELATED COMPENSATED CIRRHOSIS TREATED WITH BULEVIRTIDE MONOTHERAPY:
THE RETROSPECTIVE MULTICENTER EUROPEAN STUDY (SAVE-D)
- (06/26/23)
 
- EASL: Study of hepatitis delta virus replication markers in
anti-HBc positive patients with chronic hepatitis C
- (06/26/23)
 
- HBV/HDV Debrief at Global Hepatitis Summit 2023 - Markus Cornberg - (05/08/23)
 
- Updated Prevalence of Chronic Hepatitis B and Hepatitis Delta
Infection Among Foreign-Born Individuals in the United States
(Global Hepatitis Summit 2023, Paris April 28) - (05/01/23)
 
-
Updated Prevalence of Chronic Hepatitis B and
Hepatitis Delta Infection Among Foreign-Born
Individuals in the United States
(Global Hepatitis Summit 2023, Paris April 28)
- (04/29/23)
 
-
Treating hepatitis D with bulevirtide - Real-world experience from 114 patients
- (04/29/23)
 
- CROI:
HEPATITIS DELTA INFECTION AMONG PERSONS LIVING WITH HIV - (04/10/23)
 
-
Bulevirtide+PegIFN HBsAg response - (04/09/23)
 
- The number of new cases and deaths from
liver cancer could rise by >55% by 2040.
Global burden of primary liver cancer in 2020 and predictions to 2040 - (04/09/23)
 
- Hepatitis delta infection
among persons living with HIV in Europe
- (04/09/23)
 
-
HDV Reflex Testing Increased 5-Fold
the Absolute Numbers of Hepatitis D Cases
- (05/09/23)
 
- CROI:
BULEVIRTIDE +/- PEG-IFN IN HIV/HBV/HDV CO-INFECTED PATIENTS IN REAL-LIFE SETTINGS
- (03/22/23)
 
- Low Performance of Hepatitis Delta Virus Testing Among 2 National Cohorts of Chronic Hepatitis B Patients in the United States
- (01/24/23)
 
- Hepatitis D (Delta) Course Review: Conference Reports: USA/Global Prevalence, Mortality-HCC Impact, PWIDs, Treatment, Screening, Patient Support - (01/13/23)
 
- Durable virological response and functional cure of chronic hepatitis D after long-term peginterferon therapy - treatment duration 8-14 years - (12/29/22)
 
- Treatment With Hepcludex® (Bulevirtide) Meets Primary Endpoint and Achieves Significant Response in Chronic Hepatitis Delta Virus at 48 Weeks EASL 2022 - (12/29/22)
 
- Bulevirtide monotherapy for 48 weeks in patients with HDV-related
compensated cirrhosis and clinically significant portal hypertension - (12/12/22)
 
- AASLD: Bulevirtide Improves Health-Related Quality of Life Measured by EQ-5D VAS in Patients With Chronic Hepatitis Delta: An Exploratory Analysis of a Phase 3 Trial at 48 Weeks
- (11/15/22)
 
- AASLD: Compassionate use of subcutaneously administered
REP 2139-Mg in cirrhotic HBV / HDV co-infection
- (11/14/22)
 
- AASLD: Evaluating Hepatitis Delta Virus Disease Prevalence and Patient Characteristics
Among Hospitalized Adults in Italy
- (11/14/22)
 
- AASLD: Impact of Reflex Testing on the Delta Hepatitis Disease Burden in France - (11/14/22)
 
- AASLD: Bulevirtide Improves Health-Related Quality of Life Measured by EQ-5D VAS in Patients With Chronic Hepatitis Delta: An Exploratory Analysis of a Phase 3 Trial at 48 Weeks - (11/14/22)
 
- AASLD: OVERCOMING BARRIERS TO CARE FOR DELTA INFECTED PATIENTS - (11/14/22)
 
- AASLD: Treatment with Bulevirtide, with or without PEG-interferon, in HDV infected patients in a real-life setting. Two-year results from the French multicenter early access program - (11/14/22)
 
- AASLD: Treatment with Bulevirtide, with or without PEG-interferon, in HDV infected patients in a real-life setting. Two-year results from the French multicenter early access program - (11/11/22)
 
- AASLD: Extension of Bulevirtide Monotherapy to 72 Weeks in HDV Patients with Compensated Cirrhosis: Efficacy and Safety From the Italian Multicenter Study (HEP4Di) Interim Analysis - (11/11/22)
 
- AASLD: HDV Patient Perspective: The Impact of Disease and Current Unmet Needs - (11/10/22)
 
- AASLD: Bulevirtide, with or without peg- interferon, in HDV infected patients in a real-life setting. two-year results from the French multicenter early access program - Mark Mascolini (11/09/22)
 
- AASLD: Benefit of regular screening for hepatitis delta and subsequent cirrhosis among chronic hepatitis B carriers - (11/09/22)
 
- AASLD: Estimating Hepatitis Delta Prevalence Among High-Risk Populations (HIV, MSM, PWID) in the United States: A Systematic Review - (11/09/22)
 
- AASLD: Hep D Rate 9% in Tested California Safety-Net Group (immigrants, ethnic minorities) With HBV - Mark Mascolini (11/09/22)
 
- AASLD:
Hep D Rate 9% in Tested California Safety-Net
Group (immigrants, ethnic minorities) With HBV - Mark Mascolini (11/09/22)
 
- AASLD: Bulevirtide Monotherapy Is Safe and Well Tolerated in Patients With Chronic Hepatitis D (CHD): An Integrated Safety Analysis of 48-Week Data - (11/09/22)
 
- AASLD: The Delta Delta: Gaps in Screening Patterns, Patient
Assessment and Clinical Outcomes in Hepatitis D Virus Infection - (11/09/22)
 
- AASLD: HDV Prevalence Ranges Widely in US High-Risk Groups: Newer Data Needed - Mark Mascolini - (11/09/22)
 
- AASLD: CURE OF HEPATITIS DELTA INFECTION FOLLOWING 3 YEARS OF BULEVIRTIDE MONOTHERAPY IN A PATIENT WITH COMPENSATED ADVANCED CIRRHOSIS
- (11/08/22)
 
- AASLD:
Efficacy of Bulevirtide as Monotherapy for Chronic
Hepatitis D (CHD): Week-48 Results From an Integrated Analysis
- (11/04/22)
 
- AASLD: Evaluating Hepatitis Delta Virus Disease Prevalence and Patient Characteristics Among Hospitalized Adults in Italy
- (11/04/22)
 
- AASLD: Population adjusted prevalence of hepatitis
Delta virus in 16 countries and territories
- (11/04/22)
 
- AASLD:
HDV Load Drops, Liver Markers
Improve With Bulevirtide for 48 Weeks
- Mark Mascolini (11/04/22)
 
- AASLD:
BARRIERS TO HEPATITIS DELTA SCREENING: THE POINT OF VIEW OF FRENCH BIOLOGISTS
- (11/04/22)
 
- Time for universal screening for hepatitis D - A study describing screening patterns, characteristics, and outcomes of hepatitis D virus infection - (11/03/22)
 
-
Gilead Receives Complete Response Letter from U.S. FDA for Bulevirtide for the Treatment of Adults with Hepatitis Delta Virus - (10/29/22)
 
- ID Week:
Hepatitis D Virus and Hepatitis B Virus Epidemiology in Utah - (10/24/22)
 
-
HDV/HBV+ Immigrants in USA - (10/03/22)
 
- HDV Prevalence in USA - (10/03/22)
 
-
High HDV rates Among PWID - (09/29/22)
 
- Vir Biotechnology Announces First Patient Dosed in the Phase 2 SOLSTICE Trial Evaluating VIR-2218 and VIR-3434 for the Treatment of Chronic Hepatitis D Virus Infection - (09/29/22)
 
- HBV Meeting Paris: Strong decline of intrahepatic HDV markers and signs of liver inflammation after 48 weeks of treatment with Bulevirtide in chronic hepatitis D patients: Combined intrahepatic results from the clinical trials MYR203 and MYR301 - (09/26/22)
 
- EASL:
Characterizing of hepatitis B virus serum RNA kinetics during TDF
plus pegylated interferon alfa-2a with and without nucleic acid polymers - (07/18/22)
 
- EASL:
Compassionate use of subcutaneous REP 2139-Mg in cirrhotic HBV / HDV coinfection - (07/21/22)
 
- EASL: Bulevirtide treatment of hepatitis D in Germany: multicentre real-world experience - (07/21/22)
 
- EASL:
Improvement of liver-stiffness in HBV/HDV-coinfected patients treated with Bulevirtide - (07/21/22)
 
- EASL: Gilead to Present Latest Data From Across Liver Disease Development Programs at the International Liver Congress™ 2022 - (07/11/22)
 
- EASL: Hepatitis delta virus reflex testing in patients with hepatitis B
dramatically improves the HDV screening cascade: 10 years of
real-world experience from Avicenne University Hospital, France - (07/08/22)
 
- EASL:
Provider Factors Shaping Hepatitis Delta Screening - (07/08/22)
 
- EASL: Validation of an internal hepatitis D virus RNA Quantitative assay: Developing an assay suitable for global clinical application and clinical trials assessment - (07/08/22)
 
- EASL: Strong correlation between HBsAg, ALT and HDV-RNA levels in patients with chronic hepatitis D. Results of Phase 3 D-LIVR study. - (07/06/22)
 
- EASL: Clinical features predictive of cirrhosis in a large cohort of patients with chronic hepatitis delta infection - Insights from the D-LIVR trial - (07/06/22)
 
- EASL: Peg-Lambda HDV-RNA Kinetics Math Modeling LIMT-1 Study - (07/06/22)
 
- EASL: Rising Clinical and Economic Burden Among Hepatitis D Patients Who Attended Spanish Hospitals - (07/02/22)
 
- EASL: Impact of Patient-Related Factors on the Pharmacokinetics of Bulevirtide
- (07/02/22)
 
- EASL: Polymorphic Analysis of Bulevirtide Sequence in preS1 of Large HBsAg Across HBV Genotypes A-H - (07/02/22)
 
- EASL: Integrated Safety Analysis of 24-Week Data From Three Phase 2 and One Phase 3 Clinical Trial of Bulevirtide Monotherapy Given at 2- or 10-mg Dose Level for Treatment of Chronic Hepatitis Delta
- (07/02/22)
 
- EASL:
Peginterferon Lambda (IFN-λ) combined with Lonafarnib
diminished triphasic HDV kinetic pattern seen under IFN-λ
monotherapy: The LIFT-1 Study - (07/02/22)
 
- EASL: Mathematical modeling of HDV RNA kinetics suggests high
peginterferon lambda efficacy in blocking viral production:
Insights from the LIMT-1 study - (07/02/22)
 
- EASL: Estimating the Prevalence of Hepatitis Delta Infection among Foreign-Born Adults with Chronic Hepatitis B in the United States - (07/02/22)
 
- EASL:
Hepatitis Delta Management in the United States:
An Analysis Of All-Payer Claims Database - (07/02/22)
 
- EASL:
Healthcare Resource Utilization and Costs of Hepatitis Delta in the United States: An Analysis of All-Payer Claims Database - (07/02/22)
 
- EASL: One Third With HDV Respond to Bulevirtide Monotherapy Through 24 Weeks (2 & 10 mg) - Integrated Analysis from 2 Phase 2 & 1 Phase 3 Trials - Mark Mascolini - (07/01/22)
 
- EASL: Evidence of Past Hepatitis C and D Co-Infection in Hepatitis B Seronegative Individuals - (06/27/22)
 
- EASL: EASL 2022 HBV, HDV Wrap-Up - (06/27/22)
 
- EASL: Peginterferon Lambda (IFN-λ) combined with Lonafarnib
diminished triphasic HDV kinetic pattern seen under IFN-λ
monotherapy: The LIFT-1 Study - (06/27/22)
 
- EASL: Real life study of bulevirtide in chronic hepatitis Delta:
preliminary results of the ANRS I MIE HD EP01 HDV prospective cohort - (06/26/22)
 
- EASL: Evaluating Hepatitis Delta Virus Disease Prevalence and
Patient Characteristics Among Adults in the United States:
An Analysis of All-Payer Claims Database
- (06/25/22)
 
- EASL:
Association between Hepatitis Delta Virus with Liver Morbidity
and Mortality: A Systematic Literature Review and Meta-Analysis - (06/25/22)
 
- EASL: Response-guided long-term treatment of chronic hepatitis D
patients with bulevirtide -Results of a "real world study" - (06/25/22)
 
- EASL: No Detectable Resistance to Bulevirtide in Participants
With Chronic Hepatitis D Through 24 Weeks of Treatment - (06/25/22)
 
- EASL: Efficacy and Safety of Bulevirtide Monotherapy Given at 2 mg or 10 mg Dose Level Once Daily for Treatment of Chronic Hepatitis Delta: Week 48 Primary Endpoint Results From a Phase 3 Randomized, Multicenter, Parallel Design Study - (06/24/22)
 
- EASL: Integrated efficacy analysis of 24-week data from two phase 2 and one phase 3 clinical trials of bulevirtide monotherapy given at 2 mg or 10 mg dose level for treatment of chronic hepatitis delta - Mark Mascolini (06/24/22)
 
-
Global Hepatitis D 37% Prevalence in IVDUs
- (06/14/22)
 
- About the Phase 3 D-LIVR Study: oral Lonagarnib/rtv +/- Peg-Lambda 48 weeks
- (06/13/22)
 
-
Persistent Control of Hepatitis B Virus and Hepatitis
Delta Virus Infection Following REP 2139-Ca and Pegylated
Interferon Therapy in Chronic Hepatitis B Virus/Hepatitis Delta Virus Coinfection - (06/08/22)
 
- Safety and efficacy of REP 2139 and pegylated interferon alfa-2a for treatment-naive patients with chronic hepatitis B virus and hepatitis D virus co-infection (REP 301 and REP 301-LTF): a non-randomised, open-label, phase 2 trial - (06/07/22)
 
- Efficacy of prolonged tenofovir therapy
on hepatitis delta in HIV-infected patients - (06/07/22)
 
- PREVALENCE OF HEPATITIS DELTA VIRUS (HDV)
INFECTION IN THE UNITED STATES: RESULTS FROM
AN ICD-10 REVIEW - 25% of HDV in USA is In NYC (Bklyn, Bronx) & NYC Suburb - (06/06/22)
 
- A Phase 2 Study of Lonafarnib, Ritonavir & Peginterferon Lambda for 24 Weeks: Interim End-of-Treatment Results from the LIFT HDV Study - (05/31/22)
 
- Treatment for hepatitis delta virus with
the prenylation inhibitor lonafarnib:
It's getting closer Editorial
- (05/31/22)
 
- Optimizing lonafarnib treatment for the
management of chronic delta hepatitis: The LOWR HDV-1 study - (05/31/22)
 
-
Hepatitis D virus in 2021: virology, immunology
and new treatment approaches for a difficult-to-treat disease
- (05/31/22)
 
- Lonafarnib-A new member of the Delta Force? Editorial - (05/27/22)
 
- A phase 2 dose-finding study of lonafarnib and
ritonavir with or without interferon alpha for chronic delta hepatitis - (05/27/22)
 
- Eiger BioPharmaceuticals Announces Complete Enrollment of D-LIVR, the Largest Phase 3 Study in Hepatitis Delta Virus (HDV), Investigating Lonafarnib, the Only Oral Agent in Development for HDV - (05/27/22)
 
- HEPATITIS D INFECTION: who should be screened AASLD 2018 HBV Guidelines - (05/27/22)
 
- Gilead Submits Biologics License Application to U.S. Food and Drug Administration for Bulevirtide, an Investigational Treatment for People Living With Chronic Hepatitis Delta - (05/26/22)
 
-
Delta hepatitis within the Veterans Affairs
medical system in the United States:
Prevalence, risk factors, and outcomes - (05/26/22)
 
- Hepatitis D Changing Context Global Prevalence - (02/10/22)
 
- Gilead Submits Biologics License Application to U.S. Food and Drug Administration for Bulevirtide, an Investigational Treatment for People Living With Chronic Hepatitis Delta - (12/10/21)
 
- AASLD: Hepatitis D Delta Overview; New AASLD 2021 Treatment Studies (12/06/21)
 
- AASLD: Hepatitis D (Delta) at AASLD 2021 (12/06/21)
 
- AASLD: EFFICACY OF LONG-TERM TREATMENT OF CHRONIC HEPATITIS D
PATIENTS WITH BULEVIRTIDE - RESULTS OF A "REAL WORLD" STUDY (11/23/21)
 
- AASLD:
HDV Hospital Admissions Rare-But Sometimes Severe-in United States
- Mark Mascolini (11/20/21)
 
- AASLD: MOLECULAR AND CLINICAL EPIDEMIOLOGY OF HEPATITIS D VIRUS INFECTION IN CANADA
- (11/19/21)
 
- AASLD:
Low adherence to guidelines recommendations for hepatitis D
testing in HBsAg-positive patients leads to high undiagnosis rates - (11/19/21)
 
- AASLD: Hepatitis D-Associated Hospitalizations in the United States: 2010-2018
- (11/19/21)
 
- AASLD: Over 90% of Clinicians Ignore EACS Hep D Screening Advice - Mark Mascolini (11/19/21)
 
- AASLD:
Safety and Efficacy of 2 mg Bulevirtide in
Patients with Chronic HBV/HDV Co-Infection:
First Real-World Results - (11/17/21)
 
- AASLD: Prevalence and Characteristics of Hepatitis Delta in
the United States: an Analysis of All-Payer Claims Databases
- (11/17/21)
 
- AASLD:
ETHNIC VARIATIONS IN CLINICAL PRESENTATION AND TREATMENT
ELIGIBILITY FOR HEPATITIS DELTA VIRUS INFECTION AT A US REFERRAL CENTER - (11/17/21)
 
- AASLD: Strong intrahepatic decline of hepatitis D virus RNA and antigen after 48 weeks of treatment with Bulevirtide in chronic HBV/HDV co-infected patients: Interim results from a multicenter, open-label, randomized phase 3 clinical trial (MYR301) - (11/16/21)
 
- AASLD:
HDV seropositivity was common amongst HBsAg+ women enrolled in
WIHS. 26 (22%) of the 117 HBsAg+ women were HDV seropositive - (11/12/21)
 
- Safety and effectiveness of up to 3 years- bulevirtide monotherapy in patients with HDV-related cirrhosis - (10/25/21)
 
- EASL: Safety and Efficacy of Bulevirtide Monotherapy
and in Combination with Peginterferon Alfa-2a in
Patients with Chronic Hepatitis Delta:
24 Weeks Interim Data of MYR204 Phase 2b Study - Mark Mascolini (06/27/21)
 
- EASL: Bulevirtide With or Without PEG-IFN Shows 24-Week Activity Against Hep D - Mark Mascolini (06/27/21)
 
- EASL: Bulevirtide Monotherapy at Low and High Doses in
Patients With Chronic Hepatitis Delta:
24-Week Interim Data of the Phase 3 MYR301 Study - (06/24/21)
 
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